$ie->getButton('caption:', "Yes")->Click(1); 

#OR

my $clicker = Win32::IEAutomation::WinClicker->new();
$clicker->push_security_alert_yes();
$ie->WaitforDone;

#OR
my $clicker = Win32::IEAutomation::WinClicker->new();
$clicker->push_button_yes("Security Information");
$ie->WaitforDone;