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main::ReadDataInHash() called too early to check prototype at D:\wordm
+atch.pl line 19.

$wordfile
SSN3 CDK8 GIG2 NUT7 RYE5 SRB10 UME5
...
17170106|Perturbation of the activity of replication origin by meiosis
+ specific transcription.|We have determined the activity of all ARSs 
+on the Saccharomyces cerevisiae chromosome VI as chromosomal replicat
+ion origins in pre-meiotic S-phase by neutral/neutral 2D gel-electrop
+horesis. The comparison of origin activity of each origin in mitotic 
+and pre-meiotic S-phase showed that one of the most efficient origins
+ in mitotic S-phase, ARS605, was completely inhibited in pre-meiotic 
+S-phase. ARS605 is located within the ORF of Msh4 gene that is transc
+ribed specifically during an early stage of meiosis. Systematic analy
+ses of relationships between Msh4 transcription and ARS605 origin act
+ivity revealed that transcription of Msh4 inhibited the ARS605 origin
+ activity by removing ORC from ARS605. Deletion of UME6 {{UME6}}, a t
+ranscription factor responsible for repressing Msh4 during mitotic S-
+phase, resulted in inactivation of ARS605 in mitosis. Our finding is 
+the first demonstration that the transcriptional regulation on the re
+plication origin activity is related to changes in cell physiology. T
+hese results may provide insights into changes in replication origin 
+activity in embryonic cell cycle during early developmental stages.
.
.

#!/usr/bin/perl
use warnings;
...
    return {%list1};
}