If the location is fairly stable it should be possible to set the LD_LIBRARY_PATH via ld.so.conf (or similar). You'd still need the $SYBASE env variable so that things like the interfaces file can be found, but it would make things a lot simpler.

Of course if you need to be able to run different versions of the Sybase client libs then I suppose setting this at run-time is necessary...

Michael

PS - I didn't think anyone was still using Sybase::Simple :-)