I'm using these two...and I can talk to some IPv6 systems perfectly fine (like vCenters).

use IO::Socket::SSL qw( SSL_VERIFY_NONE );
use IO::Socket::INET;
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And later in the code...

my $ua = LWP::UserAgent->new();
$ua->ssl_opts( SSL_verify_mode => IO::Socket::SSL::SSL_VERIFY_NONE, SS
+L_hostname => '', verify_hostname => 0 );
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