To add few bits to your list,

... RedHat ships with badly packaged Tcl/Tk, (this was discussed in Tcl::Tk module development list and this makes supporting of Tcl::Tk considerably harder on RedHat)

In reply to Re^4: The Deceiver by Courage
in thread Why does a Perl 5.6 regex run a lot slower on Perl 5.8? by perldeveloper

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