I think the answer is no. It looks like someone has requested a "sticky" load-balancing option for the FastCGI implementation in lighttpd, but it hasn't been implemented. It's a pretty dangerous route to go down, making your app depend on getting the same process every time, since it hurts your scalability. If you have few users and can't partition your data, you could consider a single-threaded server approach (like POE), but most of the time it is safer to partition the data into more manageable chunks.