Describe the problem you are trying to solve. My mind reading ability is limited and somewhat spasmodic.

use strict;
use warnings;

my @hand3 = qw/KsQs JsAs/;
my @hand4 = qw/AsKc 2s3s/;
my @hand899 = qw/As3c/;

my @handsLists = (\@hand3, \@hand4, \@hand899);
##Set my hand
my $my_pocket = "AcAs";

#My cards
my %pocketCards = map {$_ => 0} $my_pocket =~ /(.{2})/g;
printf join '', keys %pocketCards, "\n\n";

for my $hands (@handsLists) {
    # If either pocket card matches the first hand card omit the hand
    @$hands = grep {! exists $pocketCards{substr ($_, 0, 2)}} @$hands;
    print "@$hands\n";
}
[download]

Prints:

KsQs JsAs
2s3s
[download]

I need it to say:

KsQs
2s3s
[download]

It any of the cards in my hand are found in either of my opponents cards, then the whole hands needs to be removed from it's @hand?.