Using POE::Component::DNS, DNSBL, Whois, HTTP. I am having the same sort of problem I suspect. Running on Suse Linux. In testing I found if I call the client functions from _start they work, if called from a button press event in the wx event loop the poe event is run but the response does not make it back to the response handler for the event. Turned on some debugging and it looked like it might be returned to the wrong session... could be wrong. Couldn't find much documentation, used example 3 for my base code. No luck so far.