in reply to Re^2: apache2 passing PERL5LIB environment to cgi
in thread apache2 passing PERL5LIB environment to cgi

That makes no sense. They should be equivalent. Both of the following should work, or both should fail.
PERL5LIB= perl -e'use lib "$ENV{HOME}/lib/perl5"; use Unicode::String +qw(utf8 latin1 utf16be);' PERL5LIB=$HOME/lib/perl5 perl -e'use Unicode::String qw(utf8 latin1 ut +f16be);'

Could you confirm or refute?