If you know the order in which they'll appear in the string being matched,
if($element[4] =~ /\Q$Homosapiens\E.*\Q$choromosome\E/)
will work fine. If you don't know the order, you want
if ($element[4] =~ /^
(?=.*?\Q$Homosapiens\E)
(?=.*?\Q$choromosome\E)
/x)
It reads: "Match homo sapiens somewhere after the start of the line, then match chromosome somewhere after the start of the line."
Update: I overlooked the obvious:
if ($element[4] =~ /\Q$Homosapiens\E/ &&
$element[4] =~ /\Q$choromosome\E/)
And since you're searching for constant strings, the following would be even faster:
if (index($element[4], $Homosapiens) >= 0 &&
index($element[4], $choromosome) >= 0)
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