In the past I've used WWW::Mechanize (along with HTTP::Recorder to create basic tests). When I've had to drive IE I've used Win32::IE::Mechanize. Corion recently released WWW::Mechanize::Firefox which is worth looking at.

Many people are these days people are using things like Selenium to test web based apps. See Using WWW::Selenium To Test Or Automate An Ajax Website from the tutorials section.

I've never used Win32::IEAutomation, and doubt that I ever will.

Update: Fixed typo tutoruals/tutorials

In reply to Re: Win32::IEAutomation vs. QTP or similar tools by marto
in thread Win32::IEAutomation vs. QTP or similar tools by vit

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