Open the two files, then read a line from each file on every iteration: 

while (my $col1 = <FILE1>) {
    chomp $col1;
    my $col2 = <FILE2>;
    print "$col1\t$col2";
}

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In reply to Re: How do you create a tab delimited txt file from two files? by almut
in thread How do you create a tab delimited txt file from two files? by elef

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