You have not given us much more useful information since you last posted about this problem, which was only a few hours ago. You keep mentioning sybperl, yet your problem relates to DBD::Sybase. After running the MakeFile.pl do you a proceed to make, make test and make install? Do you understand how to install Perl modules?

Perhaps you should read Installing Modules from the tutorials section of this site, along with How do I post a question effectively? and the PerlMonks FAQ.

Thanks

Martin