something like this if I got the question right:

ContentHandler => {
           '/' => sub { $self->{object}->Event },
},
[download]

If you want $ContentHandler->{'/'}->() to invoke the Event method on $self->{object}, you can use an anonymous subroutine like so:

ContentHandler => {
    '/' => sub {return $self->{object}->Event(@_)}
}
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By the way, calling an attribute object is probably a really bad idea.

ContentHandler => {
    '/' => $self->can('Event'},
    },
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Also (and, I think, better)

I disagree. I think it's worse. I'll explain, but let's complete the code first.

The solution from the first post:

my %handlers = (
    ContentHandler => {
        '/' => sub { $self->{object}->Event() },
       #'/' => sub { $self->{object}->Event(@_) },
    },
);

my $cb = $handlers{ContentHandler};
... = $cb->();
#... = $cb->(...);
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The solution you propose:

my %handlers = (
    ContentHandler => {
        '/' => $self->{object}->can('Event'),
    },
);

my $method = $handlers{ContentHandler};
... = $self->{object}->$method(...);
[download]

The problem is that you're getting the method of one object and you're calling it with a different object. Bad! If they aren't different object, then you have redundant code. Bad! The following would be a better version of your solution:

my %handlers = (
    ContentHandler => {
        '/' => 'Event',
    },
);

my $method = $handlers{ContentHandler};
... = $self->{object}->$method(...);
[download]

This revised solution and the one from the first post are equally good.