You don't say what OS you're on, so I'll assume you're on Linux, like me :-) .

I had a lot of problems with GD not recognizing freetype until I went back and re-installed the GD library and Freetype from the RedHat RPM's and then re-installed the GD module.

Note that there is a script that comes with the latest distribution of GD that will modify libgd (the GD library) to build itself as a dynamic library; this may or may not be needed for your system. Note that the latest version of GD.pm will only patch the latest version (1.84) of the GD library. I found that I didn't have to apply the patch; once I had installed libjpeg, freetype, libgd, zlib, and libpng the GD module installed nicely.

If you want more help, you're going to have to tell us more, including what OS you're using, which version of GD, which versions of libjpeg, libpng, libgd, and maybe freetype, as well as what problems you're having and what you've tried.