Please wrap code in <code> code tags </code>

     my $mailbox = $conn->getMailboxAvailablity (
          DOMAIN         => $UserDomainName
          MAILBOX_LIST   => $UserLoginName)
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if $mailbox is HASH(0x222b4c) then getMailboxAvailability() is returning a hash reference. You need to dereference it. The clearest way (but definately not the only way or even the best way... TIMTOWTDI) is like this:

my %dereferenced_hash = %{$hash_reference};

# of course, you can also access elements via the ref directly:
print "yeah\n" if exists $$hashref{'key2'};

# or even
print "insufficient\n" unless $hashref->{'balance'} > $request;
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But your question is a bit vague so I'm not sure what you are asking. You didn't post a complete subroutine, so I don't know what's really going on. But at least I can tell you how to deal with HASH(0x222b4c)